Access Medical Labs Blogs

Red Dye 3 Toxicity & a Long-Overdue Ban

Written by Access Medical Labs | Mar 6, 2025 10:10:17 PM

The FDA’s recent ban on Red Dye 3 highlights broader concerns about artificial food additives and their long-term health effects. Despite being prohibited in cosmetics since 1990 due to carcinogenic links in animal studies, Red Dye 3 remained in food and pharmaceuticals until January 2025, when regulatory action was finally taken. However, other controversial additives—such as Potassium Bromate, Titanium Dioxide, and Brominated Vegetable Oil (BVO)—remain legal in the U.S. despite bans in other countries.

Here's what you'll find in this article:

 

Food Additives & Our Patients 

Like many other additives, Red Dye 3 (FD&C Red No. 3) has been present in thousands of food and drug products for decades. Despite being banned from cosmetics in 1990 due to its carcinogenic effects in lab animals, it remained widespread until January 2025, when the FDA prohibited its use in food and pharmaceuticals. Banning Red Dye 3 is an important step for the FDA to take, but it highlights a larger, more concerning issue — do our patients understand what they are consuming and its effects on their long-term health, or have they put their blind faith in the FDA? 

Key Reasons for the Ban:


 

Manufacturers have until January 2027 to remove Red Dye 3 from their products, while pharmaceutical companies have an additional year to comply. However, other controversial additives like Potassium Bromate, Titanium Dioxide, Brominated Vegetable Oil (BVO) & Propylparaben, which are banned in the EU, are still allowed in the US.

The Science Behind Red Dye 3 Toxicity

The carcinogenic effects of Red Dye 3 have been studied extensively. Animal research found that exposure to the dye led to thyroid tumors, triggering legal concerns under the Delaney Clause, which mandates the removal of any food additive shown to cause cancer in humans or animals.

While some argue that the mechanism may not directly translate to human cancer risk, the FDA deemed the evidence strong enough to justify its removal from food and medicine.

Other Artificial Dyes Still in Use

Although Red Dye 3 is now banned, other synthetic dyes remain in processed foods, sparking concerns over their health effects.

Common Artificial Food Dyes and Potential Risks:

  • Red 40: Linked to hyperactivity in children and potential allergic reactions.
  • Yellow 5 (Tartrazine): Associated with behavioral changes and immune system responses.
  • Yellow 6: May contribute to adrenal and kidney issues in high doses.

Countries like the UK and EU have placed restrictions on these dyes, requiring warning labels or outright bans in certain cases. The U.S. has yet to follow suit.

How Artificial Additives Impact Health

Artificial food dyes don’t just color food—they can affect biological processes in ways that may contribute to disease.

Potential Health Effects of Synthetic Additives:


 

Identifying diet-related imbalances early can help healthcare providers guide patients toward better choices.

Related Content: GLP-1 and Gut Health: Addressing Metabolic Dysfunction

Diagnostic Testing for Food-Related Health Risks

Access Medical Labs provides comprehensive testing to assess potential health risks related to artificial additives. These advanced diagnostics go beyond routine blood work, giving clinicians deeper insights into patient health.

Key Lab Tests for Evaluating Food Additive Impact:


Moving Forward: A Proactive Approach to Patient Health

The conversation around food additives is shifting, but banning a single dye isn’t enough. Healthcare providers must take an active role in identifying and mitigating risks associated with processed foods and synthetic ingredients.

Steps for Clinicians to Support Patients:

  • Educate patients on avoiding artificial dyes and processed foods.
  • Utilize advanced diagnostics to assess metabolic and inflammatory markers.
  • Recommend dietary changes based on data-driven insights.

With Access Medical Labs next-day results and comprehensive panels, clinicians can provide personalized, preventive care tailored to each patient’s unique biochemical profile.

References:

  • U.S. Food and Drug Administration. FDA to Revoke Authorization for the Use of Red No. 3 in Food and Ingested Drugs. 2025. https://www.fda.gov
  • Center for Science in the Public Interest. Red 3: FDA Finally Bans Cancer-Causing Food Dye. 2025. https://www.cspinet.org
  • Harvard T.H. Chan School of Public Health. Food Dyes: Harmless or Harmful? 2024. https://www.hsph.harvard.edu
  • Environmental Working Group. The Hidden Health Risks of Food Dyes. 2024. https://www.ewg.org
  • National Institute of Environmental Health Sciences. Potential Impacts of Synthetic Food Dyes on Activity and Attention in Children. 2024. https://www.niehs.nih.gov
  • CNN Health. Red Dye No. 3 Is Now Banned in the US. Here's What Studies Show About More Common Dyes. 2025. https://www.cnn.com/health
  • Center for Science in the Public Interest. Food Dyes: A Rainbow of Risk. 2024. https://www.cspinet.org
  • National Center for Biotechnology Information. The Synthetic Food Dye, Red 40, Causes DNA Damage, Colonic Inflammation, and Impacts the Microbiome in Mice. 2024. https://www.ncbi.nlm.nih.gov
  • National Institute of Environmental Health Sciences. Endocrine Disruptors. 2024. https://www.niehs.nih.gov
  • National Center for Biotechnology Information. Effects of Food Additives on Gut Microbiota. 2024. https://www.ncbi.nlm.nih.gov
  • National Center for Biotechnology Information. Diet and Nutrition: The Artificial Food Dye Blue. 2024. https://www.ncbi.nlm.nih.gov